Browsing by Subject "malate synthase"
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(2019-02-12)This dissertation covers projects focused on the drug design and characterization of novel bacterial drug targets. The first project centers on acetolactate synthase (ALS), a key enzyme involved in the biosynthesis of ...
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(2008-08-03)The emergence of multidrug-resistant strains of Mycobacterium tuberculosis (Mtb) has intensified efforts to discover novel drugs for tuberculosis (TB) treatment. Targeting the persistent state of Mtb, a condition in which ...